diff --git a/setup.py b/setup.py
index 0421e307a..7896d4dd7 100644
--- a/setup.py
+++ b/setup.py
@@ -71,7 +71,7 @@ setup(
         # from requirements.txt
         'ccxt>=2.6.26',
         'SQLAlchemy>=2.0.6',
-        'python-telegram-bot>=13.4',
+        'python-telegram-bot>=20.1',
         'arrow>=0.17.0',
         'cachetools',
         'requests',