diff --git a/freqtrade/optimize/backtesting.py b/freqtrade/optimize/backtesting.py
index b26013a11..b6b7c113f 100644
--- a/freqtrade/optimize/backtesting.py
+++ b/freqtrade/optimize/backtesting.py
@@ -1400,7 +1400,10 @@ class Backtesting:
         )
         while current_time <= end_date:
             is_first = True
-            for pair in pairs:
+            # Pairs that have open trades should be processed first
+            new_pairlist = list(dict.fromkeys([t.pair for t in LocalTrade.bt_trades_open] + pairs))
+
+            for pair in new_pairlist:
                 yield current_time, pair, is_first
                 is_first = False
 
diff --git a/tests/optimize/test_backtesting.py b/tests/optimize/test_backtesting.py
index c2c6ce954..9567a2cac 100644
--- a/tests/optimize/test_backtesting.py
+++ b/tests/optimize/test_backtesting.py
@@ -1514,7 +1514,26 @@ def test_backtest_multi_pair(default_conf, fee, mocker, tres, pair, testdatadir)
 
     all_orients = [x for _, x in calls_per_candle.items()]
 
-    assert all(x == ["ADA/BTC", "DASH/BTC", "ETH/BTC", "LTC/BTC", "NXT/BTC"] for x in all_orients)
+    distinct_calls = [list(x) for x in set(tuple(x) for x in all_orients)]
+
+    # All calls must be made for the full pairlist
+    assert all(len(x) == 5 for x in distinct_calls)
+
+    # order varied - and is not always identical
+    assert not all(
+        x == ["ADA/BTC", "DASH/BTC", "ETH/BTC", "LTC/BTC", "NXT/BTC"] for x in distinct_calls
+    )
+    # But some calls should've kept the original ordering
+    assert any(
+        x == ["ADA/BTC", "DASH/BTC", "ETH/BTC", "LTC/BTC", "NXT/BTC"] for x in distinct_calls
+    )
+    assert (
+        # Ordering can be different, but should be one of the following
+        any(x == ["ETH/BTC", "ADA/BTC", "DASH/BTC", "LTC/BTC", "NXT/BTC"] for x in distinct_calls)
+        or any(
+            x == ["ETH/BTC", "LTC/BTC", "ADA/BTC", "DASH/BTC", "NXT/BTC"] for x in distinct_calls
+        )
+    )
 
     # Make sure we have parallel trades
     assert len(evaluate_result_multi(results["results"], "5m", 2)) > 0